Gvoke® Blog
Explore educational articles on topics like being prepared to treat very low blood sugar and living with diabetes.
Featured Article
February 17, 2024
Do You Have the Right Tools to Treat Very Low Blood Sugar?
The American Diabetes Association recently updated its guidelines for healthcare professionals. If you or your loved one takes medications that lower your blood sugar, such as insulin or secretagogues (sulfonylureas, meglitinides), it's important to be aware of […]
Recent Articles
July 10, 2025
Handling a Mid-Flight Diabetes Emergency: A Real-Life Experience with Gvoke HypoPen®
Leigh Fickling, Chief Operating Officer of Children with Diabetes®, shares her personal account of how she used Gvoke HypoPen® to treat her daughter’s low blood sugar emergency during a flight.
November 17, 2023
Ready, Set, Go This National Diabetes Awareness Month!
Ensure your diabetes toolkit is aligned to the standards of diabetes care for hypoglycemia
November 13, 2023
Tackling Life With Type 1 Diabetes: Shiloh Scores Big on His ‘Diaversary’
Learn how the Let’s Talk Lows campaign is helping young athletes push the limits of diabetes
All Articles
October 22, 2023
Overcoming Severe Hypoglycemia with T1D – Gvoke Success Story
Explore Tristan’s story: an 18-year-old athlete with T1D (Type 1 Diabetes) who had a severe hypoglycemic event and used Gvoke HypoPen®
July 11, 2023
7 Diabetes Management Tips for Summer
From staying hydrated to knowing the signs of low blood sugar, here’s what you need to know
May 5, 2023
Preparing your child with diabetes for a safe and fun summer camp experience
3 essential tips on how to handle medication needs, hypoglycemia risks and more
March 15, 2023
Traveling With Diabetes: 13 Tips To Be Safe and Ready
Traveling can be stressful — and if you have diabetes, there's a bit more prep work that goes into ensuring your trip runs smoothly.
March 1, 2023
2023 Hypoglycemia Guide
Managing blood sugar levels is challenging no matter how dedicated you are to your treatment plan.
February 23, 2023
I, too, can make a difference in diabetes
I didn't know anything about diabetes before I was diagnosed. I was only aware of the stigma around the condition — it happened to...
December 15, 2022
Goodbye, Glucagon Emergency Kit!
Eli Lilly and Company's Glucagon Emergency Kit has been a staple in my diabetic supply kit since I was first diagnosed with Type 1...
November 7, 2022
Here’s how you can save money on diabetes supplies before end of year
If you have diabetes, managing your day-to-day health can seem like a full-time job — not to mention staying on top of doctor's...
November 1, 2022
November is Diabetes Awareness Month — But why does it matter?
Think about a world in which no one speaks openly about their health challenges. There would be no education, no awareness, no medical..
October 28, 2022
Trick or treat: 7 tips to celebrate Halloween safely with a child living with diabetes
Spooky decorations, scary movies, pumpkin carving, cool costumes — and loads of candy. As October 31st nears, your children are...
October 13, 2022
100 years later: Celebrating the history of glucagon in treating severe lows
Learn how recent innovations have made this diabetes treatment simpler to administer
October 13, 2022
The evolution of glucagon: From emergency glucagon kits and pre-filled syringes to nasal sprays and autoinjectors
Learn about three major advances in treating severe low blood sugar (severe hypoglycemia)
September 6, 2022
Questions to ask your healthcare provider about your child’s type 1 diabetes
If you're the parent of a child with type 1 diabetes, ensuring you have the latest and most accurate information on managing the...
September 6, 2022
6 ways to help ensure a safe and successful school year for kids with type 1 diabetes
If your child has been diagnosed with type 1 diabetes, the back-to-school season is a great time to put a plan in place for the year...
May 30, 2022
Glucagon pen and more: Robin Arzon’s secret to being ready with diabetes
From blood glucose monitoring and insulin injections to emotional and physical side effects, living with diabetes comes with daily...
*Store in original sealed pouch until time of use.
Meet Gvoke HypoPen (glucagon injection)
Gvoke HypoPen is the ready-to-use rescue pen anyone can administer with confidence1,2
- Ready-to-Use Premixed and ready-to-go at a moment’s notice.3
- Simple to Administer Anyone can administer in 2 steps (pull red, push yellow)1,4 including you — in certain situations. Become familiar with how to use Gvoke HypoPen before an emergency happens and show your relatives, close friends, or caregivers where you store it and how to use it. For additional information, see Gvoke HypoPen Instructions for Use.
- Proven to Work Brings very low blood sugar back up quickly.3†
†In two clinical studies in adults, blood sugar levels that were less than 50 mg/dL increased to above 70 mg/dL or increased by at least 20 mg/dL within 13.8 minutes on average.
REFERENCES:
- Valentine V, Newswanger B, Prestrelski S, Andre AD, Garibaldi M. Human factors usability and validation studies of a glucagon autoinjector in a simulated severe hypoglycemia rescue situation. Diabetes Technol Ther. 2019;21(9):522-530.
- Meyer JM, Devona MC. U.S. Survey investigating gaps between patients and specialists in the treatment of severe hypoglycemia and impressions of the ease-of-use of liquid-stable glucagon for subcutaneous injection. Int ArchEndocrinol Clin Res. 2021;7(1):025. doi:10.23937/2572-407X.1510025
- Gvoke [prescribing information]. Chicago, IL: Xeris Pharmaceuticals, Inc.
- Gvoke HypoPen [instructions for use]. Chicago, IL: Xeris Pharmaceuticals, Inc.
important-safety-information
Indication
GVOKE (glucagon) is a prescription medicine used to treat very low blood sugar in adults and children ages 2 years and above with diabetes.
Important Safety Information
- Do not use GVOKE if you:
-
- Have a tumor in the gland on top of your kidneys, called a pheochromocytoma because of the risk of a substantial increase in blood pressure
- Have a tumor in your pancreas called an insulinoma because of the risk of low blood sugar
- Are allergic to glucagon or any inactive ingredient in GVOKE. Stop using GVOKE and seek immediate medical attention if you experience any symptoms of a serious allergic reaction such as rash, difficulty breathing, or low blood pressure
- Before using GVOKE, tell your doctor about all the medicines you take and your medical conditions, including if you have not had food or water for a long time (prolonged fasting or starvation), have low blood sugar that does not go away (chronic hypoglycemia), or have a history of a skin rash called necrolytic migratory erythema (commonly associated with glucagon-producing tumors)
- The most common side effects reported in adults are nausea, vomiting, swelling at the injection site, and headache
- The most common side effects reported in children are nausea, low blood sugar, vomiting, headache, abdominal pain, high blood sugar, pain or redness at injection site, and hives
- Inform caregivers on the Instructions for Use of GVOKE, and symptoms of severe hypoglycemia, which include unconsciousness and seizures or convulsions
- Store in original container until time of use, and at room temperature between 68°F to 77°F (20° C to 25° C)
- You are encouraged to report side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088
Please talk to your doctor and see full Prescribing Information and Patient Information Guide for GVOKE.