Gvoke® Blog
Explore educational articles on topics like being prepared to treat very low blood sugar and living with diabetes.
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Do You Have the Right Tools to Treat Very Low Blood Sugar?
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Meet Gvoke HypoPen
Gvoke HypoPen is the ready-to-use rescue pen anyone can administer1 with confidence
- Ready-to-Use Premixed and ready-to-go at a moment’s notice.2
- Simple to Administer Anyone can administer in 2 simple steps1,3,4 including you — in certain situations.
- Proven to Work Brings very low blood sugar back up quickly and safely.2†
†In two clinical studies in adults, blood sugar levels that were less than 50 mg/dL increased to above 70 mg/dL or increased by at least 20 mg/dL within 13.8 minutes on average.
REFERENCES:
- Valentine V, Newswanger B, Prestrelski S, Andre AD, Garibaldi M. Human factors usability and validation studies of a glucagon autoinjector in a simulated severe hypoglycemia rescue situation. Diabetes Technol Ther. 2019;21(9):522-530.
- Gvoke [prescribing information]. Chicago, IL: Xeris Pharmaceuticals, Inc.
- Gvoke HypoPen [instructions for use]. Chicago, IL: Xeris Pharmaceuticals, Inc.
- Meyer JM, Devona MC. U.S. Survey investigating gaps between patients and specialists in the treatment of severe hypoglycemia and impressions of the ease-of-use of liquid-stable glucagon for subcutaneous injection. Int ArchEndocrinol Clin Res. 2021;7(1):025. doi:10.23937/2572-407X.1510025
Indication
GVOKE (glucagon) is a prescription medicine used to treat very low blood sugar in adults and children ages 2 years and above with diabetes.
Important Safety Information
- Do not use GVOKE if you:
-
- Have a tumor in the gland on top of your kidneys, called a pheochromocytoma because of the risk of a substantial increase in blood pressure
- Have a tumor in your pancreas called an insulinoma because of the risk of low blood sugar
- Are allergic to glucagon or any inactive ingredient in GVOKE. Stop using GVOKE and seek immediate medical attention if you experience any symptoms of a serious allergic reaction such as rash, difficulty breathing, or low blood pressure
- Before using GVOKE, tell your doctor about all the medicines you take and your medical conditions, including if you have not had food or water for a long time (prolonged fasting or starvation), have low blood sugar that does not go away (chronic hypoglycemia), or have a history of a skin rash called necrolytic migratory erythema (commonly associated with glucagon-producing tumors)
- The most common side effects reported in adults are nausea, vomiting, swelling at the injection site, and headache
- The most common side effects reported in children are nausea, low blood sugar, vomiting, headache, abdominal pain, high blood sugar, pain or redness at injection site, and hives
- Inform caregivers on the Instructions for Use of GVOKE, and symptoms of severe hypoglycemia, which include unconsciousness and seizures or convulsions
- Store in original container until time of use, and at room temperature between 68°F to 77°F (20° C to 25° C)
- You are encouraged to report side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088
Please talk to your doctor and see full Prescribing Information and Patient Information Guide for GVOKE.