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Inform your child’s healthcare team on how to handle low blood sugar and ensure they’re ready to help

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Dear {{caregiversNameFilter}},

I hope this email finds you well. I wanted to take a moment to share some important information about my child, {{childsNameFilter}}. {{childsNameFilter}} has diabetes, so it's important to keep a close eye on their blood sugar levels throughout the day and to be prepared to step in if needed.

A serious complication of diabetes is low blood sugar which can be life-threatening if left untreated. Low blood sugar occurs when blood sugar levels drop below 70 mg/dL. Signs and symptoms may include shakiness, dizziness, confusion, combative behavior, fatigue, and difficulty speaking. My child's symptoms are: {{symptomsFilter}}.

Here is what to do for low blood sugar:

1. Address it immediately.

If {{childsNameFilter}} is below 70 mg/dL (mild) or below 54 mg/dL (moderate), it is recommended to treat promptly with 15 grams of oral fast-acting carbohydrates (e.g., glucose tablets, fruit snacks, juice). Then, retest in 15 minutes and repeat the process until their target blood sugar level is reached.

In these cases, low blood sugar snacks or glucose tablets for {{childsNameFilter}} can be found in {{locationSnacksFilter}}.

2. Recognize when something more is needed.

There are times when eating or drinking isn't enough to correct low blood sugar and it becomes an emergency. For example, if {{childsNameFilter}} is:

  • Unable or unwilling to eat or drink
  • Feels like passing out
  • Passes out or has a seizure

In emergencies like those stated above, they have a ready-to-use rescue pen called Gvoke HypoPen® to treat very low blood sugar. It can be found in {{locationGvokeFilter}}. I ask that you please watch this instructional video to learn how to use it: https://bit.ly/3TAIsv9. After using Gvoke HypoPen, make sure to turn them on their side if they are passed out and call for emergency help.

If there are any questions or if you need further clarification on helping {{childsNameFilter}}, please feel free to contact me. Thank you sincerely for your attention to this matter and your support.

Best Regards,
{{gardiansNameFilter}}
Indication and Important Safety Information⁠—⁠Read More

Indication

GVOKE (glucagon) is an antihypoglycemic agent indicated for subcutaneous use for the treatment of severe hypoglycemia in adult and pediatric patients aged 2 years and older with diabetes.

Important Safety Information

  • GVOKE is contraindicated in patients with:
    • Pheochromocytoma because of the risk of substantial increase in blood pressure
    • lnsulinoma because of the risk of hypoglycemia
    • Prior hypersensitivity reaction to glucagon or to any of the excipients. Serious hypersensitivity reactions have been reported with glucagon, including generalized rash, and anaphylactic shock with breathing difficulties and hypotension
  • GVOKE may stimulate the release of catecholamines from the tumor. If patient develops a substantial increase in blood pressure and a previously undiagnosed pheochromocytoma is suspected, 5 to 10 mg of phentolamine mesylate intravenously has been shown to be effective in lowering blood pressure
  • In patients with insulinoma, administration of glucagon may produce an initial increase in blood glucose; however, administration may stimulate exaggerated insulin release from an insulinoma and cause hypoglycemia. If a patient develops symptoms of hypoglycemia after a dose of GVOKE, give glucose orally or intravenously
  • Patients with insufficient hepatic stores of glycogen may not respond to GVOKE for treatment of severe hypoglycemia. Insufficient hepatic stores of glycogen may be present in conditions such as states of starvation, or in patients with adrenal insufficiency or chronic hypoglycemia
  • A skin rash called necrolytic migratory erythema (NME), has been reported post-marketing following continuous glucagon infusion and resolved with discontinuation of the glucagon. GVOKE is not approved for continuous infusion. Should NME occur, consider whether the benefits of continuous glucagon infusion outweigh the risks
  • Most common adverse reactions reported in adult patients were nausea, vomiting, injection site edema raised 1 mm or greater, and headache
  • Most common adverse reactions reported in pediatric patients were nausea, hypoglycemia, vomiting, headache, abdominal pain, hyperglycemia, injection site discomfort and reaction, and urticaria
  • Patients taking concomitant beta-blockers may have a transient increase in pulse and blood pressure. In patients taking concomitant indomethacin, GVOKE may lose its ability to raise glucose or may produce hypoglycemia. GVOKE may increase the anticoagulant effect of warfarin

Please see full Prescribing Information for GVOKE.